'Skipping' drug marks step forward for muscular dystrophy
An experimental drug designed to fit a DNA patch in a flawed gene has cleared an important hurdle in tests on boys struck by a tragic muscle-wasting disease, a British study on Monday says.
View ArticleFirst targeted treatment success for Duchenne Muscular Dystrophy
(Medical Xpress) -- A team led by scientists at UCL, funded by the Medical Research Council (MRC) and AVI BioPharma, have made an important breakthrough in the development of a treatment for Duchenne...
View ArticleWhen nerve meets muscle, biglycan seals the deal
A protein that has shown early promise in preventing the loss of muscle function in mouse models of Duchenne muscular dystrophy, has been found in a new study to be a key player in the process of...
View ArticleNew model of muscular dystrophy provides insight into disease development
Muscular dystrophy is a complicated set of genetic diseases in which genetic mutations affect the various proteins that contribute to a complex that is required for a structural bridge between muscle...
View ArticlePreclinical muscular dystrophy data shows promise
Cedars-Sinai Heart Institute researchers have found that an experimental compound may help stem the debilitating effects of muscular dystrophy by restoring normal blood flow to muscles affected by the...
View ArticleResearchers describe a key mechanism in muscle regeneration
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL) have described a new selective target in muscle regeneration. This is the association of alpha-enolase protein and plasmin. The...
View ArticleNew design guidelines simplify development of targeted therapies for muscular...
The dystrophin protein offers critical support to muscle fibers. Mutations affecting dystrophin's expression cause the muscle-wasting disease muscular dystrophy. In Duchenne muscular dystrophy (DMD),...
View ArticleResearchers utilize genetically corrected stem cells to spark muscle...
Researchers at the University of Minnesota's Lillehei Heart Institute have combined genetic repair with cellular reprogramming to generate stem cells capable of muscle regeneration in a mouse model for...
View ArticleGenetic editing shows promise in Duchenne muscular dystrophy
Using a novel genetic 'editing' technique, Duke University biomedical engineers have been able to repair a defect responsible for one of the most common inherited disorders, Duchenne muscular...
View ArticleDiscovery one step closer to treatment for Duchenne muscular dystrophy
(Medical Xpress)—A University of Alberta researcher has pinpointed a mutation that brings the medical community another step closer to treating those who suffer from a fatal type of muscular dystrophy.
View ArticleDiscovery of new form of dystrophin protein could lead to therapy for some...
Scientists have discovered a new form of dystrophin, a protein critical to normal muscle function, and identified the genetic mechanism responsible for its production. Studies of the new protein...
View ArticleNew hope in fight against muscular dystrophy
Research at Stockholm's KTH Royal Institute of Technology offers hope to those who suffer from Duchenne muscular dystrophy, an incurable, debilitating disease that cuts young lives short.
View ArticleBacterial defense mechanism targets duchenne muscular dystrophy
Duke researchers have demonstrated a genetic therapeutic technique that has the potential to treat more than half of the patients suffering from Duchenne Muscular Dystrophy (DMD).
View ArticleDuchenne muscular dystrophy is a stem cell disease
A new study from The Ottawa Hospital and the University of Ottawa is poised to completely change our understanding of Duchenne muscular dystrophy and pave the way for far more effective treatments.
View ArticleStem cell gene therapy could be key to treating Duchenne muscular dystrophy
Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and Center for Duchenne Muscular Dystrophy at UCLA have developed a new approach that could eventually...
View ArticleNew research increases understanding of Duchenne muscular dystrophy
A new paper, co-written by faculty at Binghamton University, State University of New York, increases the understanding of Duchenne muscular dystrophy (DMD)—one of the most common lethal genetic...
View ArticleGene transfer corrects severe muscle defects in mice with Duchenne muscular...
Duchenne muscular dystrophy is a rapidly progressive disease that causes whole-body muscle weakness and atrophy due to deficiency in a protein called dystrophin. Researchers at the University of...
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